Yes, some seeds are better than others. The main reason I buy from catalogs are for the varieties they offer and the fact that I know those seeds are well-handled, fresh and tested for germination. Now if you can buy name-brand seeds at Home Desperate or the like then go for it! Local nurseries are going to carry good stock for you to select from. Just watch the dates, all seed packages have dates on them, you want this year's seeds (2008 at this point), not seed packaged for use in 2006. With experience you'll begin to figure out which seeds last and can be saved over from year to year (I've always had good luck with bean seeds, even three year old seeds, peas are ok, carrots aren't, some lettuces, etc. ).