Digits had a link a year or two ago that showed the projected yield for tomatoes based on letting them fall to the ground, staking, trellissing, or caging. I think those were the four options. Falling to the ground yielded the least, and the yield grew from there. That's been a while, but I think the reason falling to the ground was worst was because you lost more to rot and such. Think of the others as if you are looking at them from a helicopter. The stake would be a single dot. The trellis would be a line. A caged system would have length and width, giving them more space to grow. Maybe one dimension, two dimensions, and three dimensions.
If you cage instead of trellis, your rows need to be a little further apart.
I use cattle panels on both sides, leaving an opening between them of about 24" this year. I'm not saying that is perfect. More space might work out better. I had 18" last year and it certainly was not enough. I mulch real well, partly because I really like mulch, partly to control moisture, but also to control weeds. Even with the big openings in the cattle panels, it is a little awkward to get in there to weed. Plus a disease, blight, can get spalshed up on the vines from the ground when it rains. If you have a good mulch, that dirt does not get splashed up on the vines so mulch is a protection against disease.
When I use two panels for tomatoes, one on each side, I don't use guy wires on the supports. I do run wire between the two panels at a few points to sort of tie them together so they act as a unit, but I have not had trouble with the wind blowing them over. Trellisses are different.
I use bolt cutters and remove the bottom horizontal wire on the panel. That way I can push the bottom of the cattle panel into the ground, anchoring it. You still need the T-posts or some type of supports, but that anchoring in the ground really helps.
I tie some vines to the cattle panels initially, but not all that many. I sort of weave the vines through the openings as they grow. The cattle panel is just over 4' high, so the indeterminates will grow out the top and bend back over to the ground. I'm extending mine up an extra 2 feet this year to see how much that helps and what problems that might cause.