You recently posted a problem with moles. Skunk and moles both favor the same food -- grubs in the lawn. If you see triangular digs in your grass, that is a sign that skunks are hunting grubs. Once you manage to get rid of the grubs, the moles and the skunks just might move on as well.
I wish you all the luck in the world. I didn't like having Cee Cee dancing with the skunk in the brush pile and feared she'd get skunked again. She's come home reeking three different times (a slow learner, I suspect).